Deadly Dog Parasite Discovered in the Colorado River

Our lab recently discovered a parasite lurking in the southern half of the Colorado River that could be deadly to dogs and other animals. We were first contacted by a veterinarian in the Los Angeles County Health Department in January 2023 because several vets in the area were starting to report that dogs they had treated seemed to be sick with canine shistosomiasis. At least one dog had even died before the sickness could be identified. As the veterinarians questioned the dog owners, it seemed that many of the dogs had been in contact with the Colorado River. Canine shistosomiasis is caused by a parasite, so the Los Angeles County Department of Public Health reached out to us to see if we could provide any information that could be useful.

Our lab identified a possible location along the Colorado River where the parasite could be hiding, so we visited the shores of the Colorado in Blythe, California, several times and collected hundreds of snails. Snails are known to be vectors of canine shistosomiasis. (A vector is a host that carries a disease from one individual to the next.) If we could find the parasite in the snail, then we could confirm that this parasite was indeed in the Colorado River.

After months of collecting snails and testing, we finally discovered that not only was there one snail species that carried canine shistosomiasis, but there were actually two different snail species in the Colorado River in Blythe carrying this disease.

Canine shistosomiasis is mostly harmless to humans. It can cause a rash that’s commonly known as “swimmer’s itch.” This rash usually clears up on its own after a few days because the parasite can’t actually survive in humans. However, this same parasite can infect dogs and other animals, like raccoons and even horses. And it thrives in these animals, causing sickness and potentially even death if left untreated. It’s a tricky parasite, though, because it can sit dormant in the animal for months before making itself known. By this time, most dog owners or horse owners may not associate their trip to the Colorado River with their pet’s new sickness. Vets in the area also may not know to test for this disease.

Our hope is that we can inform the public of the dangers of visiting the Colorado River right now with pets and animals. If you do visit the river and your pet later becomes sick, make sure your vet tests for canine shistosomiasis.

Our work has recently been featured in the following news articles: NBC Los Angeles, Gizmodo, LA Times, and KYMA of Yuma, Arizona.

Dog Parasite Discovered in California

After being recruited by local veterinarians to help find the source of a parasitic infection in southern California, we identified two species of snails, Galba cubensis and G. humilis in the Colorado River in California. We also identified that some of those snails were indeed carrying Heterobilharzia americana, the fluke that causes canine schistosomiasis. Our finding is the first report of the presence of this flatworm parasite in Southern California.

New Entomopathogenic Nematode, Steinernema adamsi, Described

S. adamsi emerging from hostWe have characterized a new species of entomopathogenic nematode (EPN). This EPN was isolated from Thailand and falls within the Longicaudatum clade, being closely related to Steinernema hermaphroditum. The nematode was named after Dr. Byron Adams, who was Dr. Dillman’s undergraduate mentor and who introduced Dr. Dillman to EPNs in 2003. Steinernema adamsi is the newest EPN to be described and has much to teach us about how nematodes parasitize insects. It may also be useful in biological control. A UCR press release has additional information.

sPLA2 from S. carpocapsae modulates insect immunity

Sophia and Ogadinma led a research project which was just published illustrating that a secreted phospholipase A2 enzyme released from S. carpocapsae modulates insect immunity. The paper also included other members of the lab. This is the third individual protein from S. carpocapsae that we have shown to have immunogenic properties in insects. 

ShK-Domain-Containing Proteins Modulate Host Immunity

Parasitic nematodes release a wide variety of proteins into their hosts to manipulate host biology. One family of proteins that is released by Steinernema carpocapsae are the ShK-domain-containing proteins. It was previously not known how these proteins function during a nematode infection. Graduate student Aklima Lima reported that one of these proteins released from S. carpocapsae during infection modulates host immunity by decreasing host resistance to infection. In addition to evaluating how the protein affects fly survival, she also employed some behavioral assays to assess fly health in a more sensitive way. The results were published this week in Pathogens and represents the first published results from Aklima’s graduate work.

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